It comprises a series of purpose-constructed bus-only roadways, as well as reserved lanes on existing city streets and portions of Highway 403, that together form a continuous 18 km (11 mi) route spanning most of the city from Winston Churchill Boulevard in the west to the junction of Highways 401 and 427 in the east on the border with Toronto.

In the 1990s, a serious proposal intended to build a "transitway" from Ridgeway Drive at the very western edge of the city;[1] this was eventually revised to its current state, with construction beginning in November 2010.

The longer eastern busway begins east of Hurontario Street, paralleling Highway 403 to Cawthra Road and then following Eastgate Parkway on its north and west side to Eglinton Avenue, and Eglinton on its north side to the eastern terminus at Renforth Drive at the boundary with Toronto.

[14] With the opening of the first phase on November 17, 2014, MiWay adjusted three of its routes to use the eastern section of the corridor, initially operating Monday through Saturday from 4:30 AM to 10:30 PM.

All stations are wheelchair-accessible, have heated waiting areas, and similar to the Züm service operated by Brampton Transit, loading platforms designed for level boarding.

"It should have been built along Burnhamthorpe, the heart of the city.”[29] Looking at the Erin Mills station, Amar Shubhanan Lad comments that "Pedestrian and cycling connections in particular are poor, inaccessible and uninviting to try."

Lad also found that a previously existing pedestrian shortcut to the station had been closed at local resident's request.

[30] "The biggest problem with the Transitway is the location of the stops, which are not in walkable areas" as noted by Jason Slaughter, a Dutch-Canadian YouTuber.