The company traces its roots to the Moss Point & Pascagoula Railroad, which was formed in 1894 and began operating between its namesake cities the next year.

Initially a very small railroad with only four miles of track, it grew significantly starting in 1902 when it was purchased by the owner of a sawmill in Moss Point.

During World War I, the company again struggled financially, and the owners filed with the Interstate Commerce Commission to abandon the entire line in 1920.

[2][3] The railroad served a variety of industries including shipbuilding on the coast, lumber mills, and a number of factories.

[3] The company significantly grew its business during the 1950s, adding new customers such as a paper mill, chemical plants, and a pet food manufacturer.