The gravel road was designated as a state route around 1960, from US 61 to MS 4.

[1] MS 308 started at an intersection with US 61 near Maud, and it traveled eastward along Dubbs Road.

[2] At Limerick Road, MS 308 turned north and continued through farmland.

[3] The route ended at an intersection with MS 4 southeast of White Oak.

[1][2] The road was maintained by the Mississippi State Highway Commission (MSHC) and Tunica County, as part of the state highway system.