It travels to the north-northeast along Prather Road into Kansas City proper.

Before crossing Parvin Road, the route curves northeast, then before passing under Interstate 35 it curves back to due north, at which point it becomes Antioch Road.

The route crosses Englewood Road into the city limits of Gladstone, continuing on from N.E.

Then Route 1 curves back to the north, becoming N. Indiana Avenue.

[2] The highway was one of the original 1922 highways in Missouri and it originally ran from the Arkansas state line south of Noel to the Iowa state line north of Rock Port.