The highway was mentioned in the title of David R. Holsinger's four-movement piece "One Day In a Small Town...".

The highway then passes through Gilliam, crosses the Missouri River, then enters Glasgow.

As the highway exits Glasgow, Routes 5 and 240 turn off of Route 87 and head east-northeast (despite being signed as a southbound direction) until meeting the other end of Business Loop 240, after which the duplex turns east.

The duplex later turns south-south east and meets the southern terminus of Route 3.

Though cardinal direction signs read "East," it actually runs south from its parent route, taking the Lewis and Clark Trail with it.

Spur Route 240 officially enters Rocheport, just before crossing a bridge over Moniteau Creek where it also crosses the Howard-Boone County Line, then ends at Route BB (Third Street), which takes the Lewis and Clark Trail with it, while Spur Route 240 continues south as Central Avenue which leads to a portion of the Katy Trail State Park.