Mistresses is a British drama television programme that follows the lives of four female friends and their involvement in an array of illicit and complex relationships.

Katie Roden (Sarah Parish) is a GP who, at the beginning of series 1, is having an affair with John Grey, a terminally ill patient whom she later helps commit physician assisted suicide.

Distraught, he confides in Katie, unaware of her role in his father's life and they begin a reluctant relationship as she struggles with her grief and guilt over helping John die.

Katie also meets Jack and Megan's friend, fellow surgeon Dan Tate (Mark Umbers), with whom she strikes up a relationship.

Katie ends the affair before she is discovered but Dan witnesses a final kiss between the pair and decides to move to Australia to take up a medical post he's been offered.

Trudi also starts selling her home-made cakes at a local deli where Lucas (Sean Francis), the owner, is clearly keen on her.

Concerns over Richard's finances lead Trudi to discover his secret - that his wife, who he had claimed had abandoned him and Amy, is in a residential home for patients suffering early-onset Alzheimer's.

Whilst he embarks on a friendship and brief affair with Katie, Trudi is flattered by the attentions of an investor in the cake business, Chris (Vincent Regan), and frustrated by what she feels is a lack of support from Richard.

She enjoys a one-night stand with Chris but soon comes to regret it and is distraught when Richard is killed in a car accident whilst on his way to meet Katie at the train station, where he intends to talk about Trudi's infidelity.

Jessica Fraser (Shelley Conn) is an event planner who has had a string of lovers including her boss, Simon (Adam Astill), and who doesn't get involved in committed, long-term relationships.

Jessica believes the marriage is a strong one but is shocked by how jealous she is when she realizes that Mark has been engaged in a long term sexual relationship with his assistant, Carrie, (Preeya Kalidas).

Jessica makes her feelings known, and though Mark realises she is unhappy he can't bring himself to be faithful to one woman, causing them to split.

Things become complicated when she meets Tom McCormack (Thomas Lockyer), an older businessman who is unsatisfied with their one night stand and begins to pursue Siobhan, showing up at her home and becoming a client at work in a bid to insert himself into her life.

Locations used for filming other than Bristol: The wedding sequences in episode 1 of series 2 were shot in the gardens and cloister of Iford Manor, near Bradford-on-Avon, Wiltshire.

In Australia it was broadcast on the Seven Network from 29 April 2008,[3] New Zealand on TV One from 5 November 2008, USA on BBC America from 20 February 2009, and Ireland on RTÉ One from 23 June 2009.

[6] Studio Dragon and Chorokbaem Media announced a South Korean remake of the series, Mistress, set to air in April 2018.