Mitch Unrein (born March 25, 1987) is an American former professional football defensive tackle.

In a game against the Tampa Bay Buccaneers on December 2, 2012, Unrein lined up for the first time as at the fullback position.

[2] He proceeded to catch his first career touchdown pass from quarterback Peyton Manning.

[10] In 2017, Unrein started eight out of 12 games played, recording a career-high 32 tackles and 2.5 sacks.

[12] On March 16, 2018, Unrein signed a three-year, $10.5 million contract with the Tampa Bay Buccaneers.

[18] His older brothers Mark[19] and Mike,[20] both played college football for the University of Northern Colorado Bears.