Mitvim activities include original research, policy planning workshops, task teams, expert working groups, and public opinion polls.

[5] Mitvim prioritizes engagement with the Knesset and government ministries, in an effort to address questions related to Israel foreign policy.

[7] In October 2020, following the normalization agreement between Israel and the UAE, Mitvim established an Israeli-Emirate dialogue track with an institute in Abu Dhabi.

[9] Mitvim runs an intensive summer course, “Domestic and Regional Aspects of the Israeli-Palestinian Peace Process,” for graduate students of Syracuse University's Institute for National Security and Counterterrorism.

The conference, titled "Opportunities for Israel's Foreign Relations Towards 2018," included a keynote address by Avi Gabbay, Chairman of the Labor Party and Zionist Union.

Conferences often address the findings of Mitvim's annual Israeli Foreign Policy Index, synthesized with data from public opinion polling done over the course of the year.