The Regent Theatre is a live music venue and historic former movie theater in the Downtown section of Los Angeles, California.

Opened as the National Theatre in 1914, it is the oldest remaining theater building on South Main Street.

Following its initial status as a first-run filmhouse, it began screening second-run programming in the 1920s amidst a widespread decline of the vicinity's entertainment scene in favor of the newer Broadway Theater District.

The building remained unused until 2006 when a local developer acquired the lease and used it occasionally for performing arts events.

[3] Knitting Factory Entertainment and Artist & Recreation provided renovation services for lessee Spaceland Productions beginning in 2012.