Grant Morrison wanted to use Moira on their run on New X-Men as the team scientist,[citation needed] but she was killed prior to the start of the series causing them to use Beast (Henry "Hank" McCoy) instead.

House of X #2 retconned established continuity, revealing her to be a mutant with the ability to reincarnate within her own timeline; on her death, she is returned to the moment she is conceived with full knowledge of her previous lives.

Her knowledge of potential futures, when divulged to Professor X and Magneto, leads to the formation of the nation-state of Krakoa and the new status quo for the X-Men books following House of X and Powers of X.

She was the longest running human associate of the X-Men and was Professor Charles Xavier's colleague, confidante, and also once his fiancée, having met and fallen in love with him while they were postgraduates at Oxford University.

She was married to her old flame, the late politician Joseph MacTaggert which caused delays with her former engagement to Xavier: Joe had proved to be an abusive husband; Moira separated from him after he beat her into a week long coma and, as it is implied, raped her, leaving her pregnant.

Moira appeared at Xavier's call to act as "housekeeper" for the team while they were on missions (a position that required her to demonstrate her proficiency with an M16 rifle against a demon within hours of her arrival).

Proteus' escape and eventual destruction at the hands of Colossus and the X-Men left Moira in a position of ethical compromise again: though Banshee stopped her from cloning her son, she saved his genetic structure on disk to allow herself the future option of bringing him back.

[12] When a mysterious virus began attacking the genetically engineered mutate population of Genosha, Moira volunteered her services as a geneticist and was forced to watch as the former slaves were decimated by disease.

Mystique, partly assisted by Sabretooth, then destroyed Muir Island, de-powered Wolfsbane with the power nullifier once developed by Forge, and brutally injured Moira.

Moira's students—Vulcan (Gabriel Summers, the lost brother of X-Men Cyclops and Havok), Petra, Darwin, and Sway—were apparently all killed, and Xavier suppressed even the memory of them from his own students to keep them from going back to save them.

[24] During the "Chaos War" storyline, Moira MacTaggert is brought back from the afterlife, alongside the fallen X-Men members John Proudstar, Banshee, three Madrox dupes, and Sophie and Esme Cuckoo, after what happened to the death realms.

One of the Post-Humans, the Librarian, explains his cohort's plan to Moira and Logan: Homo novissima hopes to be absorbed by the Phalanx and "ascend" to the hive mind of a Dominion system, thus gaining control over time and space.

Knowing that the Trask family is responsible for creating the Sentinels, and how that technology will be used to overtake mutantkind, Moira applies not to Oxford but to the military, joining the British Air Force to learn all she can about killing.

As most of the mutant senior leaders die or disappear, the remaining ones approve the creation of the Sinister breeding pits on Mars, where Essex trains his chimeras to serve as soldiers on Krakoa upon reaching the age of 16.

Apocalypse's forces eventually split into two teams: one group attacks the Temple of Concordance while the other heads into Nimrod's vast archives to extract vital information about its origins.

[27] Moira then replaced herself with the decoy at some point, allowing her to continue working from the shadows with Xavier and Magneto to make the dream of a peaceful mutant existence a reality.

Moira has since taken residence in "No-Place", a blackout zone within the newly sovereign, living island nation of Krakoa with Xavier and Magneto, the only people aware of her being alive and her actual role in this grand plan.

Xavier and Magneto comply to Moira's demands and gathered the data and DNA while also calling a vote for new members in the Quiet Council, which can be done at any time under Krakoan law, in order to oust Mystique.

At the same time, they cause so much death and destruction for Orchis that Karima Shapander aka Omega Sentinel and Nimrod personally lead the attack force and find the two mutant leaders in their site.

Dubbing Phalanx-Woverine as Omega Wolverine, Moira confronts the genius techno-utopian businessman and billionaire Arnab Chakladar, founder of Epiphany, whose commercial memory drives served as a prosthetic cerebrum and a step towards true bio-tech synthesis, in his safehouse and explained her multiple lives and how mutants have already defeated death.

After that, she tries to use the neutralizer gun on herself in order to get her powers back, so she could kill herself and erase the current time-line, but it does not work because Moira's infiltration of Krakoa doesn't go unnoticed, and Professor X mentally reaches out to her.

Later as the second annual Hellfire Gala is near, multiple anti-mutant adversaries looms ominously over the festivities, leading to the Avengers needing to step in to protect the Krakoa's, Moira notes that while the two teams have fought before, pretty often in fact, neither has ever truly beaten the others.

With the public increasingly sympathetic to their cause, the X-Men teamed up with the Avengers and the Fantastic Four to take out Orchis, eliminating in the process Nimrod, the greatest threat to mutantkind's continued existence, but unable to capture Moira who's able to escape.

With over four trillion Sinister-coded mutants in the galaxy by this point, Essex harvested their minds to ascend beyond time and space, only to discover a Sinister Dominion already existed, and rejected him.

Moira and Orchis took many steps in the weeks to come for their chess match against mutantkind and when the third Hellfire Gala happened, Nimrod and Feilong's Stark Sentinels introduced themselves to the mutant race.

With a dagger dipped in Blightswill and her own mechanical immunity to telepathy, Moira plunged her weapon into Jean Grey's back, taking another Omega-class mutant off the board and breaking Charles Xavier's heart as his first and most beloved student died slowly.

However, in the 2019 storyline, "House of X", Moira was revealed to actually be a mutant with the ability to reincarnate herself upon death, reverting to the moment of her initial conception with all the memories she experienced in her previous lifetimes from as early as in utero.

Her lifetimes have armed her with significant experience, including expertise in the fields of anthropology and genetics, firearms mastery, and leading various mutant survival movements until their eventual downfall.

Purely mechanical by design, Moira's new body is equipped with holographic projectors that make her appear human to the naked eye, except for the occasional pulse of red light from her optics.

When the reality-hopping Exiles caught Proteus's attention, Moira emerged from hiding to warn them about her son, who was intrigued by their presence and desired to ruin the realities they attempted to fix.