The issues were cover dated April 2004 to March 2005, and were all written by Justin Gray and Jimmy Palmiotti.
The stories take place in the present (of the publication dates), with flashbacks to the events surrounding The Monolith during the Depression Era.
In the present the reader is introduced to Alice Cohen as she receives her inheritance from her recently deceased grandmother.
One of the first things that Alice discovers is a walled off section in the basement from which a voice calls to her to read stories.
The events leading to The Monolith's creation begin when the textile factory that Alice works in is firebombed by the Mafia.
Deciding that Peter's death should not be in vain Alice and her friends create a golem using knowledge Rabbi Rava has learned.
Seeing their creation is out of control Alice, Rabbi Rava, and Han seal The Monolith in a bootlegger tunnel located beneath the house they live in.
In the present the lawyer overseeing Alice's grandmother's will gets her a job working for NYCAT (the New York Citizen's Assistance Team).
While Alice is dealing with her first day at this job, The Monolith leaves the house to seek out a demon that lies hidden beneath a church.
Giovanni Zavatinni (the current guardian) is seeking to rid himself of this curse and aides The Monolith in the fight against L'ono Nero.
Alice is also taken to the church but is set free by the guardian An arsonist calling himself the Incinerator begins to target the Arab-American and Muslim American community of New York City.
His first target is a home for recent Arab Muslim immigrants in Bedford-Stuyvesant that was built through the efforts of NYCAT and the Wayne Foundation.
The Rabbi is forced to create a golem made of iron for these mobsters after they threaten to kill Alice if he doesn't.
This call leads Alice to a modern slave ring headed by a group of corrupt police officers.
[1] In 2019, Monolith, Alice and Tilt were used in PaperFilm's graphic novel Painkiller Jane: Trust The Universe, where they team up to rescue a friend's little sister from a human trafficking ring.