Monomoy Regional High School serves approximately 625 students in grades 8-12 from the towns of Chatham and Harwich.

Construction of the high school was completed in early 2014 and officially opened in September 2014.

[6] With the departure of Monomoy, Mashpee is left as the South Shore League's lone representative from Cape Cod.

During the Fall 2023 season, both Girls Field Hockey[7] and Boys Soccer[8] advanced to the MIAA State Finals.

Listed below are the sports offered at Monomoy Regional High School: