It contains an area of mangroves and numerous islets or cays, including Borracho, Muerto, Sombrero, Sal, Las Animas, and Peraza.

White sand beaches on these cays include Mero, Paiclas, Los Juanes, Playuela, Tucupido, Azul and Boca Seca.

It stands amid the surrounding coastal environment of Tertiary-period coral origin, belonging to the Capadare - Agua Linda limestone geological formation.

The vegetation is quite varied and is closely associated with geomorphological positions, the most important subsets being the coast, coastal lagoons, marshes, saline shoals, cays and shallow seabed.

Red, black, white and buttonwood mangroves are the dominant vegetation and landscape of the park and form a unit that preserves the ecologically fragile balance of the coastline in an area of about 4,500 ha.

Because Morrocoy National Park and Wildlife Refuge Cuare are located in the same geographic area, it is inferred that the avifauna has a similar composition.

Land mammals are found mainly in the Chichiriviche Hill area, including brocket and white-tailed deer, anteaters, crab-eating foxes, howler monkeys, three-toed sloths, opossums, pacas, agoutis and peccaries.

Fish breeding in the park include grouper, snapper, corvina, tarpon, snook, toadfish, school shark, sardines, mackerel, grunt, barracuda and the many species that inhabit the coral reefs.