Most consists of eight municipal parts (in brackets population according to the 2021 census):[2] The name Most means 'bridge' in Czech.

From the end of the 12th century, the Hrabišic dynasty began to colonize the territory and established here a stronghold.

The city developed rapidly and benefited from its advantageous location near the kingdom's borders and on an important road.

[7] In 1515, the worst fire in its history hit the city, damaging the church from 1253–1257 and the town hall.

In the second half of the 16th century, the crisis was deepened by crop failures, loans to the king, plague, famine, further fires and Turkish wars.

[7] In 1639–1648, during the Thirty Years' War, the city was occupied by Swedish troops because of the Hněvín Castle.

Industrialization began and the turning point was the construction of the railway in 1870, which brought connection with coal outlets.

The last quarter of the 19th century saw a rapid increase in the number of inhabitants and newly built apartments, and there was an influx of the Czech population.

Under German occupation from 1938 until 1945, the city was administered as a part of the Regierungsbezirk Aussig of the Reichsgau Sudetenland.

In 1944, there was a subcamp of the Flossenbürg concentration camp providing forced labor in coal mines outside Most.

German population was expelled in accordance with the Potsdam Agreement and the city was resettled by Czechs.

[8] In 1964, the Czechoslovak Communist government decided to demolish the historic Most due to the expansion of coal mining, including the Gothic city centre, the brewery founded in 1470, the 1910 theatre, and the cemetery established in 1853.

Newly built, standardized blocks of flats (paneláks) followed brutalist architecture common for that era.

The destruction of Most brought monetary profit to the state as coal was mined in the locality for an estimated 3 billion CSK.

It is a large lignite power plant with a total installed electrical output of 239 MWe, built in 1955–1958.

[16] In addition to mining, heavy industry and chemistry were developed in Most, but in the 21st century they are replaced by services in the composition of the city's economy.

In addition to the main railway station, the Most-Kopisty and Třebušice stops are also located in the municipal territory.

[19] It includes a planetarium located on the roof sphere, a cinema and numerous rooms and halls.

The city sold the building to the private sector in 2010 and has been subject to numerous replacement and refurbishment proposals.

[20] The new theatre was planned for the new city centre from the late 1960s but construction didn't commence until 1979 and was opened on 7 November 1985.

The city is now represented by FK Baník Most-Souš, playing in the 3rd tier of Czech football.

The area with the race track was created during the reclamation of the landscape and is also used for other sports and cultural events.

Today the Church of the Holy Spirit has been desecrated and exhibitions and classical music concerts take place in its premises.

[28] Among the other monuments are the building of the Regional Museum in Most, Neorenaissance fountain, plague column with the sculptural group of St. Anne, set of Stations of the Cross, and Jewish cemetery in Souš.