It served the town of Mount Bryan.
Mount Bryan railway station opened in 1880.
The station consisted of a station master's office, goods shed, a cloakroom, cattle and sheep yards, cream and egg shed and wheat stack yard.
The station closed for regular passenger use on 13 December 1986.
The last passenger train, a Steamrail Victoria tour using Victorian locomotive R761 used the station on 6 June 1987.