Mount Pleasant Regional Airport (IATA: MPS, ICAO: KOSA, FAA LID: OSA) is a city-owned, public-use airport located three nautical miles (6 km) south of the central business district of Mount Pleasant, a city in Titus County, Texas, United States.

[1] It is included in the National Plan of Integrated Airport Systems for 2011–2015, which categorized it as a general aviation facility.

[2] Mount Pleasant Regional Airport covers an area of 284 acres (115 ha) at an elevation of 364 feet (111 m) above mean sea level.

[1] For the 12-month period ending August 13, 2010, the airport had 13,200 general aviation aircraft operations, an average of 36 per day.

At that time there were 47 aircraft based at this airport: 72.3% single-engine, 23.4% multi-engine, and 4.3% jet.