In 2009, Mount Sinai Medical Center began an affiliation with Columbia University, allowing for students and patients to treat, research, and study between Miami and New York City.

[2] Mount Sinai purchased Miami Heart Institute in 2000 for $75 million on the theory that consolidating the two hospitals would slowly ease the competition of the two nearby facilities and improve their image.

[3] Many of Miami Heart Institute's Doctors, nurses and skilled technical staff were transferred over to Mount Sinai as part of the acquisition.

In February 2012, Mount Sinai Medical Center sold the Miami Heart Institute building, which was redeveloped into a luxury condo under the Ritz-Carlton brand.

[4] As of 2020[update], Mount Sinai Medical Center is the only hospital and largest employer on Miami Beach.