Mount St. Joseph University was established by the Sisters of Charity of Cincinnati, Ohio, a religious congregation that traces its roots to Elizabeth Ann Seton, North America's first canonized saint.

Men's sports: Baseball, basketball, cross country, football, golf, lacrosse, soccer, tennis, track and field, volleyball, wrestling and Esports.

Women's sports: Basketball, cheerleading, cross country, dance, golf, lacrosse, soccer, softball, tennis, track and field, volleyball and Esports.

In late 2014, incoming freshman basketball player Lauren Hill was suffering from an inoperable brain tumor and facing the possibility of dying before the end of that year, and wished to play in one college game before her death.

The game was the start of a charitable fundraising campaign that, by the time of her death in April 2015, raised over $1.5 million for research into the specific cancer from which Hill was suffering.

Since her death, MSJ and Xavier have teamed up for an annual season-opening women's basketball doubleheader, the Lauren Hill Tipoff Classic, at Cintas Center.