One of its main missions was to "Americanize" Lutherans by teaching courses in the English language instead of German, unlike the nearby Capital University in Columbus, Ohio.

[4] The first class originally consisted of eight students at the beginning of the academic year, but grew to seventy-one by the end.

With a faculty of one professor and two tutors, classes were held in Springfield, Ohio, in a church on land that was donated.

[7] For decades, Hamma and Wittenberg were associated with the local English-speaking regional Lutheran synods in the Midwest.

The education department occupies a second building at 49 East College Avenue that formerly contained the administration offices of the Springfield Public City Schools, but is now owned by Wittenberg University.

Until 1967, Carnegie Hall was exclusively a science building until the athletics department began holding conferences and classes in the same area.

It also serves as a popular breakfast and lunch location for students, as it includes a vendor on the first floor that can be used with the Wittenberg meal plans.

A building behind Recitation Hall serves as the university's police and security headquarters, the campus switchboard and the transportation office.

[19] Wittenberg University teams participate as a member of the National Collegiate Athletic Association's Division III.

[24] Wittenberg ended the 2009 fall sports season ranked 16th among more than 430 NCAA Division III schools in the Learfield Sports Directors Cup standings, administered by the National Association of Collegiate Directors of Athletics (NACDA)[25] The university has over 50 active, registered student organizations, ranging from student-led organizations to Academic and Honor Societies.

[26] Wittenberg University opened the Hagen Center for Civic and Urban Engagement on 24 September 2008, to help coordinate community service projects.

It has included the Peer Advocate program since 2016, providing advocacy services for survivors of power-based violence (regardless of gender identity).

The William C. McClain Center for Diversity is located on Alumni Way and is named for the first African American to graduate from Wittenberg University in 1934.

[28] WUSO simulcasts the Dayton classical station WDPR on weekday mornings, filling the remaining hours with news, politics, sports, food, and music shows.

The team also records news stories for WUSO and writes press releases for the university website.

The Torch is Wittenberg University's weekly student-run newspaper; it is staffed by news reporters, editors, features writers, sportswriters, designers and photographers.

[30] In 2020, due to the COVID-19 pandemic, The Wittenberg Torch ended the print copies of their newspaper and moved to a fully digital format.

Each residence hall includes TV-lounges, ping-pong tables, vending machines, cooking appliances, student printers, and laundry facilities.

It is centrally located on campus and in close proximity to the Benham-Pence Student Center, Thomas Library, and Blair Hall.

Ubuntu, or "I am because we are," was created for students who seek an inclusive and diverse space of living, in specifically Black and Brown cultures.

The Polis House was formerly the international residence hall on campus, and is now the Tiger Pride Themed Living Community, beginning in 2021.

The main floor of the student center houses Post 95 which offers four different options, including Champ City Grill, Ward & Wood Subs, The Pour, and Ezra's (serving prepared-to-order stirfry).

Breakfast and lunch are also served on weekdays in the Barbara Deer Kuss Science Center's "Simply To Go" cafe.

Beginning in the 2024-2025 school year, all students (Freshmen-Senior) are required to select a meal plan along with their housing accommodations.

[33] Wittenberg has an active Greek Life community with ten fraternities or sororities currently chartered on campus.