It was managed by the Cwm Taf Morgannwg University Health Board.

The facility has its origins in the Mountain Ash Cottage Hospital which was established in 1910.

[1] The current structure was opened by Lord Aberdare as the Mountain Ash and Penrhiwceiber General Hospital in 1924.

[2] It joined the National Health Service as Mountain Ash General Hospital in 1948[3] but, after services transferred to the Ysbyty Cwm Cynon, the general hospital closed in 2012.

[4] It was demolished in 2017 after a suspected arson attack that destroyed the main building.