[1] The name mouse avatar or avatar mice was originally coined by the Spanish National Cancer Research Center [2] and was subsequently popularized by the journals Nature[3] and Science,[4] the Mayo Clinic[5] and The New York Times[6] among others.
[7][8] Generally, mouse avatars involve three steps, as follows:[9] The tumor is obtained by surgical resection.
If this happens, the avatar mice may guide the oncologist to choose the most efficient chemotherapeutic treatment.
This process can be repeated several times to obtain a large number of avatar mice from a single patient.
The response of the tumors in the avatar mice to the various chemotherapeutic regimens is examined and the most efficient one is chosen.