The Slovene participating broadcaster, Radiotelevizija Slovenija (RTVSLO), organised the national final Evrovizijska Melodija 2006 in order to select its entry for the contest.

Fourteen entries competed in the national final where "Plan B" performed by Anžej Dežan was selected following the combination of votes from a five-member jury panel and a public televote.

[2] The broadcaster has traditionally selected its entry through a national final entitled Evrovizijska Melodija (EMA), which has been produced with variable formats.

[3][4] Fourteen songs competed in a televised show where the combination of points from a five-member expert jury and a public televote determined the winner.

The televoting groups and the expert jury each assigned points as follows: 1–8, 10 and 12, with the song that received the highest overall score when the votes were combined being determined the winner.

[6] An expert committee consisting of Jaka Pucihar (composer), Rok Lopatič (music producer), Jernej Vene (music editor for Radio Val 202), Mitja Ciuha (Eurovision expert) and Mario Galunič (television presenter) selected fourteen artists and songs for the competition from the received submissions.

On 4 February, Dežan performed "Mr Nobody" during the Maltese Eurovision national final Malta Song for Europe 2006.

[16] Dežan also completed promotional activities in Macedonia in late April, including a performance during the Sitel TV programme Zvezdena Planeta.

[17] According to Eurovision rules, all nations with the exceptions of the host country, the "Big Four" (France, Germany, Spain and the United Kingdom) and the ten highest placed finishers in the 2005 contest are required to qualify from the semi-final on 18 May 2006 in order to compete for the final on 20 May 2006; the top ten countries from the semi-final progress to the final.