It is the only album featuring bassist Tyson Maiko, who left the band in 2008.

The first single from the album was "We're All Dying", which got its first radio play on June 18, 2007.

A song frontman Tom Thacker has originally written for this album, entitled "Panic Attack", has become the title track from Sum 41's fifth studio album Screaming Bloody Murder, which was the band's first album to be recorded with Thacker as lead guitarist.

The album cover art is a reprint of Calavera Oaxaqueña[4] by Mexican folk artist José Guadalupe Posada On September 10, 2007, Muertos Vivos was announced for released the following month; alongside this, "We're All Dying" and "Prescription" were made available for streaming through the band's Myspace profile.

[5] Muertos Vivos was released on October 30, 2007 through Aquarius Records.