[3] The Mugere is joined by the Mahangwe River from the right (north) before Nyankere colline, where there is an electric power station.

It flows in a west-northwest direction, and is joined from the left (south) by the Nyarubenga at Nuamusenyi.

It continues west under the RN3 highway and enters Lake Tanganyika through an area of marshland just north of Ramba.

The area around the Mugere River is densely populated, with 530 inhabitants per square kilometer as of 2016.

[9] In January 2013 an expert in geomorphology warned that there was a risk that the Muhere dam in the Giheta colline would collapse.

[10] While the Ruziba Market was being rebuilt, in 2015 it was temporarily relocated to a site beside the Mugere River.

[13] For some time, rubble and gravel were extracted by cooperatives from the bed of the river for use in construction in Bujumbura.