Muhammad Nsereko is an Independent member of the Ugandan parliament, and Lawyer who has represented the Kampala Central Division constituency since 2011.

[2] In 2011, Nsereko contested the Kampala Central Division constituency on the ruling National Resistance Movement (NRM) political party ticket.

He outlined several areas of disagreement with his political party, including (a) the proposed conversion of Mabira Forest Reserve into sugar plantations (b) the proposed scrapping of bail for some crimes (c) he abhors the rampant corruption of the ruling class (d) he deplores the high unemployment rates among the country's youth and (e) he supports the restoration of presidential term-limits which was scrapped in 2005.

[4] That decision was overturned by the Supreme Court on 30 October 2015, and Nsereko and his colleagues returned to parliament as independents.

[5][6] Muhammad Nsereko was re-elected to the 10th parliament (2016 to 2021), as an independent and he continues to be a leader against the ongoing amendment to change the constitution and remove the presidential age limit.