Originally designed to transport troops at a high speed and then land them on the beach, they have since expanded their roles to include interdiction, surface warfare, and search and rescue.

[1] In September 2017, the Department of National Defense (DND) released a tender to procure an additional three MPAC vessels based on the Mk 3 platform which will be fourth batch.

[16] In May 2010, the MPACs first saw combat when they were used to extract Precinct Count Optical Scan (PCOS) machines in Basilan under heavy mortar fire from rogue Moro Islamic Liberation Front (MILF) rebels attempting to sabotage the election.

[23] In September 2015, an MPAC participated in the 2015 PAGSISIKAP Fleet-Marine Amphibious Exercise in Ternate, Cavite by landing Philippine Marine Corps personnel into the beach.

The Radz-Auna was found with 1,500 5 kg sacks of smuggled Sugar with an estimated worth of PHP 3.15 million, and was immediately escorted to the Zamboanga Port and turned over to the Bureau of Customs.

[27] In April 2018, the MPAC Mk 2 (BA-485) participated in the interception of the Mongolian registered M/V Diamond 8 vessel near the Olutanga Island in the province of Zamboanga Sibugay which was later found to be attempting to smuggle Php 67 million worth of rice.

[30] In April 2020, MPAC Mk 3 (BA-493) delivered relief goods for Patients Under Investigation (PUI) and Persons Under Monitoring (PUM) for the coronavirus pandemic in the remote Towns of Mapun and Turtle Islands in Tawi-Tawi.

[32] On November 3, 2020, two MPAC Mk 3 (BA-491) and (BA-493) were involved in a high speed intercept of a boat carrying seven Abu Sayyaf terrorists off the coast of Parang, Sulu.

[33][34] In February 2021, the MPAC Mk 3 (BA-494) intercepted and caught the F/B Princess Arlyn off the coast of Sulu which was carrying 360 Cases of smuggled imported cigarettes worth Php 17.3 million on its way to Cotabato City from Indonesia.

[35] In July 2021, the MPAC Mk 2 (BA-485) rescued 17 People from the Jungkung-type Boat named Friendly off the Coast of Patikul and Luuk in Sulu after it capsized due to big Waves and strong Winds from the bad Weather in the area.