The Cercanías Murcia/Alicante commuter rail network connects Murcia del Carmen with Alicante railway station and Águilas through lines C-1 and C-2.

AVE and Avlo high speed services use the Madrid–Levante high-speed rail network to connect Murcia to Madrid.

Talgo services also operate to Valencia Nord and Barcelona Sants.

Since 20 December 2022 the AVE high-speed rail system is serving Murcia via the Madrid–Levante high-speed rail network[2][3] and construction works are ongoing for the Murcia–Almería high-speed rail line with extensive modifications for the train station in order platforms and track to be relocated underground.

[6] The new station is expected to be finished by 2024 at a cost of 11 million euros.