[2] Their comic New Men was nominated for the Nommo Award for Best Graphic Novel.
[4] He and artist Dotun Akande met at Redeemer's University, where they began making comics together.
[6] In 2019, he and Akande released New Men,[7] a "soft biopunk thriller" set in Africa in the year 2030.
[11][12][13][14][15] In 2024, it was announced that they would release their next comic, Akogun: Brutalizer of Gods, through Oni Press.
[16][17][18] In May 2024, Ayodele was announced as the writer for the upcoming Storm series set during the X-Men: From the Ashes relaunch with artist Lucas Werneck.