He was the eldest son of Isa Khan, probably by his first wife Fatima Bibi, who was the daughter of Ibrahim Danishmand.
[3][4] Khan's grandfather, Kalidas Gazdani, accepted Islam under the guidance of Ibrahim Danishmand.
[5] Sulaiman married the Sultan's daughter Syeda Momena Khatun and received the Zamindari of Sarail which passed onto Musa Khan's father.
[7] After the death of his father in 1599, Musa Khan inherited the throne of Sonargaon, gaining the vast territory of Bhati and becoming the chief of the Baro-Bhuiyan landlords of Bengal.
[8] He was then dethroned and imprisoned by Islam Khan Chishti, the army general of Emperor Jahangir and Subahdar of Bengal Subah.