[2] Musanze is Rwanda's most mountainous district, containing the largest part of the Volcanoes National Park, and its head office at Kinigi.

Five of the eight volcanoes of the Virunga chain (Karisimbi, Bisoke, Sabyinyo, Gahinga and Muhabura) are within the district boundaries.

It is also in this district that most of Rwanda's mountain gorillas are found, making it the most popular tourist destination in the country.

[3][4] Musanze district is divided into 15 sectors (imirenge): Busogo, Cyuve, Gacaca, Gashaki, Gataraga, Kimonyi, Kinigi, Muhoza, Muko, Musanze, Nkotsi, Nyange, Remera, Rwaza and Shingiro.

[5] Irish potatoes are mainly grown in Burera, Musanze, Nyabihu and Rubavu districts and this program is expected to harmonize the Irish potato trading locally and turn it into export-oriented business[6][7]