It is located at Mizzou North (former Ellis Fischel Cancer Center) on Business Loop 70 West in Columbia, Missouri.

The galleries reopened on April 19, 2015 at Mizzou North after their previous building was closed due to nuclear radiation.

Selections from the permanent collection of more than 14,000 works of art and archaeological objects are displayed in five galleries.

Casts of Greek and Roman sculpture, on loan from the Department of Art History and Archaeology, occupy a gallery on the first floor.

The collection contains objects from a wide range of cultures with Greek, Roman, and Near Eastern art works and artifacts being especially strong.