The museum processes and makes accessible documents on the development of nature and society of the southern part of the Danube lowland and of Hungarian nationality culture in the Slovak Republic.
[3] In 1913, Budapest University professor Dezső Hültla had built the Cultural Palace, which is today the museum headquarters.
Due to lack of staff and space to grow, the museum did not undergo a lot of development until the 1970s.
Beginning in 1975, the museum began renting more space to show temporary exhibitions, and has continued this practice.
The museum focuses on collecting and preserving the history and development of the Komárno region, as well as the area surrounding it.