The 3G Slide was unveiled by T-Mobile USA on May 4, 2010, pre-orders began May 23, 2010 and the device went on sale June 2, 2010.

In early April 2011, HTC released the Android OS 2.2.1 ("Froyo") update file.

"Genius" is a custom voice command and text-to-speech system powered by Dragon Dictation technologies.

The myTouch 3G Slide features a 3.4 inch, 320x480 pixel HVGA-resolution TFT capacitive multi-touch enabled LCD screen.

Features include a new optical trackpad which replaces the physical trackball found on the older 3G; a 5-megapixel low-light camera with LED flash; built-in GPS with A-GPS support; Bluetooth 2.1 with A2DP and AVRCP support; Wi-Fi 802.11 b/g; a three-axis accelerometer; proximity sensor; 3.5mm standard headphone jack; and a microSD slot, preloaded with an 8 GB microSDHC card.