[1][2] The consortium seeks to solve structures of proteins that are of great interest to the TB biology community.
[3] A major goal of the consortium is to have a putative function for every ORF in the TB genome.
[citation needed] As of June 2006, the TB Structural Genomics Consortium consists of 430 active members in 148 laboratories from 83 institutions across 15 countries.
The consortium has five core facilities (located at Lawrence Livermore National Laboratory, Los Alamos National Lab, Lawrence Berkeley National Laboratory, University of California, Los Angeles and Texas A&M University) that carry out an increasing fraction of routine tasks such as protein production, crystallization and X-ray data collection.
[citation needed] The five core facilities available to consortium members provide services for cloning, expression, and purification of proteins as well as crystallization and subsequent diffraction and data analysis of protein crystals.