The myoepithelial cells may be spindled, plasmacytoid, eithelioid or clear.

Tubules or epithelium are absent, or present in a small amount (<5%) by definition.

Tumours with myoepithelial cells and a large amount of tubules are classified as pleomorphic adenomas (which must also contain the characteristic chondromyxoid stroma, which is normally absent in myoepithelioma).

Benign myoepithelioma are treated with simple excision.

Malignant myoepitheliomas are excised and have been treated in the past with dacarbazine but are prone to both metastasis and re-occurrence.