Myograph

A wire myograph is a type of laboratory apparatus that can measure the contractility of luminal tissue segments smaller than 2 mm in diameter.

[5] Diagrams of the first ever wire myograph were revealed by Mulvany and Halpern in their 1976 paper "Contractile properties of small arterial resistance vessels in [...] rats".

[6] The group based the design of this apparatus on a technique developed by Bevan and Osher to measure arterial contractility ex vivo.

[7] Development of the wire myograph was significant because it allowed researchers to estimate the effect of novel drugs on blood pressure for the first time.

[3] These wires are attached to two opposing stainless steel jaws which secure tissue in place throughout the culture period.

A myograph recording from a pendulum myograph after an induced contraction. The upper line (m) represents the curve traced by the end of the myograph lever in connection with a muscle after stimulation of the muscle by a single induction-shock.