At the 2016 census, the locality had a population of 744, of whom 393 lived in its town centre.

[3][2] Myponga is located within the federal division of Mayo, the state electoral district of Mawson, and the local government area of the District Council of Yankalilla.

[8][7][1] Before British colonisation of South Australia, the Kaurna people occupied the land from the Adelaide plains and southwards down western side of the Fleurieu Peninsula, including Myponga.

[9] Geoff Manning reports that "according to H.C. Talbot it is derived from the Aboriginal word miappunga – 'divorced wife'", and Norman Tindale concluded that it probably meant "vegetable food place, from [mai] and [pangkara], a term applied to swamps & lagoons".

However linguist Rob Amery of the University of Adelaide and Kaurna educator Jack Buckskin concluded that it was just a name and does not have a literal translation.