In 1997 she founded the Professionist Center for Human Rights (CeProDH), which defends and assesses laid off and unemployed workers and intervenes against repression and impunity, and the Justicia Ya!

[9] Bregman participated among the appellants of the first trial made since the re-opening of the cases of crimes against humanity perpetrated by criminals of the Argentinian Dictatorship, that of former Buenos Aires police chief Miguel Osvaldo Etchecolatz, where Justicia Ya!

Myriam Bregman was also an appealing lawyer during the oral trial against Cristian Federico Von Wernich in La Plata (2007), accusing him of crimes against humanity committed in Campo de Mayo, the “Floreal Avellaneda” case in San Martín, Province of Buenos Aires (2009), "Seré Mansion" case (against Buenos Aires and Mar del Plata repressors in 2008), among others.

[3] In 2016 Carlos Blaquier and Ledesma executives sent her an intimidatory letter as she prepared to travel to Jujuy to receive complaints of grave human rights violations in the province of then-governor Gerardo Morales.

[11][10] Bregman denounced that she received phone call threats in her office after her intervention in the Labour and Budget Commission where she questioned the first employment bill because she considered that it was a measure to legalise outsourcing.

She also took the opportunity to criticise the Catholic Church and La Plata Archbishop Héctor Aguer, who "has as their transmission band local governors, who negotiate with women's rights".