Myrtle Beach High School originally shared a facility with all the lower grades in Myrtle Beach's public schools in a building occupying a city block bounded by N. Kings Highway, Oak Street, 5th Avenue North, and 6th Avenue North.

MBHS was relocated to its present site on Robert Grissom Parkway between 29th and 38th Avenues North.

Myrtle Beach High School offers the following sports: baseball, basketball, cheerleading, cross country, football, golf, soccer, softball, swimming, tennis, track and field, volleyball, lacrosse, and wrestling.

The Seahawks have won many state championships in school history, including: Football: 1980, 1981, 1983, 1984, 2008, 2010, 2013 and 2018[4] Boys Basketball: 1965, 1987, 2002, and 2008.

The unit competes in Academic, Drill, Rifle, Color Guard and Orienteering competitions throughout both North and South Carolina.