She was later a schoolteacher and a professor at two historically black colleges and universities in Kansas and Missouri.

[3] Myrtle Craig's father persuaded her to attend the Michigan Agricultural College (M.A.C.)

[3] After graduating from the Michigan Agricultural College, Craig spent her next forty years teaching African American youth in Kansas and Missouri.

From 1907 to 1910 she taught at Western University in Quindaro, Kansas, then taught domestic art for two years at Lincoln Institute in Jefferson City, Missouri, during which time she exhibited at the 1911 Missouri State Fair, winning a blue ribbon and other prizes for work in domestic arts.

She then taught for three years at Sumner High School in Kansas City, Kansas; returned to teaching at Lincoln Institute from 1917 to 1922; taught elementary school in Fulton, Missouri, from 1922 to 1934; and again at Lincoln Institute from 1934 to 1947.