The N80 road is a national secondary road in Ireland that runs southeastwards from its junction with the N52 and R443 in the town of Tullamore in County Offaly, to the N30 at Ballynahallin, just north of Enniscorthy in County Wexford, a distance of 114.683 km.

Some of the worst bends may have been removed through the years and some junctions improved, but general pavement quality is rather poor.

Earlier works of note on the N80 include: The Tullamore bypass[2] is a new 14 km (8.7 mi) single carriageway upgrade to the N52.

A spur designated part of the R443 was constructed from the northern section of the route to the Tullamore Western Relief Road forming a near complete orbital route around Tullamore.

The N80 now terminates at the N52 junction on the bypass; traffic heading for Athlone now takes the N52 north to the M6 motorway at Kilbeggan.