[5] EST profiling of NBPF19 shows it to be ubiquitously expressed in most human tissues at unremarkable amounts.

It is expressed in relatively higher amounts in the skin, lymphoid organs (lymph nodes, spleen) and the gonads (ovary, testes).

[8] The protein product of the NBPF19 transcript is composed of 3,843 amino acids and weights 440.5 kD.

[8][9] It contains 45 DUF1220 domains of unknown function but that have been linked to evolutionary changes and generally decrease in number in species increasingly evolutionarily distant from humans.

The protein is extensively phosphorylated on serine, threonine and tyrosine residues in a repetitive pattern seen in the figure to the left.