One of NEXT for AUTISM's most well known accomplishments was opening the first charter school in New York to exclusively serve autistic students.

The event features performances from various comedians frequently including Jon Stewart, Conan O'Brien, Tina Fey, Amy Poehler, and George Clooney.

In June 2013, they opened the Center for Autism and the Developing Brain on the New York-Presbyterian Westchester campus to provide clinical services to autistic people throughout their lives.

[4] In April 2021, Mark Rober and Jimmy Kimmel announced they would be hosting a live stream in support of NEXT for AUTISM.

[6] The organization has received criticism for its endorsement of Autism Speaks and applied behavior analysis.