Most of NY 141 is a two-lane road that serves residential and commercial areas; however, the southwesternmost 0.2 miles (0.3 km) is a four-lane divided highway.

Over the next 1.5 miles (2.4 km), NY 141 closely parallels the railroad's Harlem Line, serving its Hawthorne station as the road heads north.

[3] As Commerce Street, NY 141 continues to head to the northeast, passing by a line of businesses in an otherwise residential area between the hamlets of Hawthorne and Thornwood.

The route eventually enters the latter's central business district, where the Saw Mill Parkway and the Harlem Line turn northwestward toward the center of the nearby village of Pleasantville.

NY 141 continues on a northern track however, veering off of Commerce Street onto Franklin Avenue, then becoming known as Broadway again as it heads through mostly residential areas on its way into the eastern portion of Pleasantville.

[3] The alignment of NY 141 between Fort Washington Avenue in Hawthorne and the Pleasantville village line was constructed up to state highway standards during the early 20th century.

[10] In Hawthorne, a grade crossing on Broadway with the New York Central Railroad Harlem Division existed just north of the railroad station at the intersection with Elwood Avenue until 1951, when the New York State Department of Public Works realigned the route away from Broadway onto a bridge over the tracks south of the station leading to a wye at Elmwood Avenue.