Hilker was on camera for numerous German and international magazines and fashion companies and shot commercials for, among others, Clearasil and C & A.

In the ARD feature film Zimmer mit Auntie, she played the female lead role alongside Jutta Speidel and Ingo Naujoks.

This was followed by numerous series appearances and other roles in television films such as Rosamunde Pilcher's The Other Woman with Rupert Everett and Natalia Wörner.

[3] In 2018, Hilker joined the cast of the AMC TV series The Walking Dead, playing a character named Magna.

[5] On March 12, 2024, Hilker announced on Instagram that she and her longtime boyfriend are expecting their first child in November 2024.