Nafisa is also related to the Bangladeshi freedom fighter and soldier Bir Pratik Akhtar Ahmed.

[4] She has also studied vedanta taught by Swami Chinmayananda, who started the center Chinmaya Mission of World Understanding.

She has acted in several Bollywood films, the notable ones being Junoon (1979) with Shashi Kapoor, Major Saab (1998) with Amitabh Bachchan, Bewafaa (2005), Life In A... Metro (2007) and Yamla Pagla Deewana (2010) with Dharmendra.

On 5 April 2009, she contested the Lok Sabha election from Lucknow on the Samajwadi Party ticket after Sanjay Dutt's disqualification by the Supreme Court on the basis of a prior conviction.

[4] After marriage, she chose to stop working and focus on their children: daughters Armana and Pia and son Ajit.