Nagykálló (Yiddish: קאלוב, romanized: Kaliv) is a small town in Szabolcs-Szatmár-Bereg county, in the Northern Great Plain region of eastern Hungary.

After the Ottomans burnt the town in 1556, the citizens built a stone castle for defence.

After his death they moved to Hajdúböszörmény, but Nagykálló remained an important industrial centre.

In 1630 George II Rákóczi occupied the town and issued the Proclamation of Independence here.

Francis II Rákóczi attacked the castle on July 29, 1703 (first battle of the war for freedom) and occupied it the following day.