Nancy Killefer (born 1953) is an American government consultant and political figure.

She was nominated for the Chief Performance Officer position in the Obama administration in 2009.

Nancy Killefer is a Director in the Washington, D.C., office of McKinsey & Company, the global management consultancy.

She left McKinsey & Company from 1997 to 2000 to serve as Assistant Secretary for Management, CFO, and COO at the United States Department of the Treasury.

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