[citation needed] For his A-Level education, he attended Busoga College Mwiri in Jinja District.

[citation needed] In 1997, he went back to Makerere University, graduating in 2000 with a Master of Arts in Economics followed by a Bachelor of Laws in 2006.

From 1998 until 2000, he worked as the senior principal revenue officer and acting chief internal auditor at URA.

[1] In 2001, he entered Uganda's elective politics by contesting the Budadiri County West parliamentary constituency.

[1][3] Honorable Nathan Nandala Mafabi is also the Vice-Chair of The Parliamentary Network on the World Bank & International Monetary Fund.