In 2016, she starred in the critically acclaimed film Moonlight, a performance that earned her a number of accolades, including nominations for the Golden Globe, BAFTA, and Academy Award for Best Supporting Actress.

Harris was appointed an Officer of the Order of the British Empire (OBE) in the 2017 New Year Honours for services to drama.

Her mother Carmen Harris (sometimes credited as Lisselle Kayla),[1][2] having emigrated from Jamaica to London as a child with her parents, has worked as a screenwriter on EastEnders and as a healer.

[3] Harris' fashion designer father Brian Clarke emigrated from Trinidad to the UK, and has British, Grenadian, and Guyanese ancestors.

[10][11][12] Harris has appeared in television and film since she was nine, including a starring role in the remake of the science fiction series The Tomorrow People.

[18][19] She played Elizabeth Lavenza in Danny Boyle's stage production of Mary Shelley's Frankenstein for the National Theatre from 22 February to 2 May 2011.

[20] She played the lead role in The First Grader, directed by Justin Chadwick, which was premiered on 18 May 2011 in the Seattle International Film Festival.

[28] In 2021, Harris reprised her role as Eve Moneypenny in the James Bond film No Time to Die and starred as Frances Barrison / Shriek in Venom: Let There Be Carnage.

The condition progressed severely into her teen years which necessitated a spinal fusion; it took her a month to recover fully and she had to learn how to walk again.

[34][35][36]In addition to numerous acting awards, Harris was appointed an Officer of the Order of the British Empire (OBE) in the 2017 New Year Honours, for services to drama.